Taking forward the World TB Day 2016 theme 'Unite to End Tuberculosis' for the WHO Africa Region.
Identifieur interne : 000135 ( Main/Exploration ); précédent : 000134; suivant : 000136Taking forward the World TB Day 2016 theme 'Unite to End Tuberculosis' for the WHO Africa Region.
Auteurs : Francine Ntoumi [Allemagne] ; Pontiano Kaleebu [Ouganda] ; Eusebio Macete [Mozambique] ; Sayoki Mfinanga [Tanzanie] ; Jeremiah Chakaya [Kenya] ; Dorothy Yeboah-Manu [Ghana] ; Matthew Bates [Zambie] ; Peter Mwaba [Zambie] ; Markus Maeurer [Suède] ; Eskild Petersen [Oman] ; Alimuddin Zumla [Royaume-Uni]Source :
- International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [ 1878-3511 ] ; 2016.
Descripteurs français
- KwdFr :
- Afrique (épidémiologie), Antituberculeux (usage thérapeutique), Humains, Mycobacterium tuberculosis (), Organisation mondiale de la santé, Prévalence, Santé mondiale, Séropositivité VIH, Tuberculose (), Tuberculose (épidémiologie), Tuberculose multirésistante (), Tuberculose multirésistante (épidémiologie), Éradication de maladie.
- MESH :
- usage thérapeutique : Antituberculeux.
- épidémiologie : Afrique, Tuberculose, Tuberculose multirésistante.
- Humains, Mycobacterium tuberculosis, Organisation mondiale de la santé, Prévalence, Santé mondiale, Séropositivité VIH, Tuberculose, Tuberculose multirésistante, Éradication de maladie.
English descriptors
- KwdEn :
- Africa (epidemiology), Antitubercular Agents (therapeutic use), Disease Eradication, Global Health, HIV Seropositivity, Humans, Mycobacterium tuberculosis (drug effects), Prevalence, Tuberculosis (epidemiology), Tuberculosis (prevention & control), Tuberculosis, Multidrug-Resistant (epidemiology), Tuberculosis, Multidrug-Resistant (prevention & control), World Health Organization.
- MESH :
- chemical , therapeutic use : Antitubercular Agents.
- drug effects : Mycobacterium tuberculosis.
- epidemiology : Africa, Tuberculosis, Tuberculosis, Multidrug-Resistant.
- prevention & control : Tuberculosis, Tuberculosis, Multidrug-Resistant.
- Disease Eradication, Global Health, HIV Seropositivity, Humans, Prevalence, World Health Organization.
Abstract
Tuberculosis (TB) remains a global emergency, with an estimated 9.6 million new TB cases worldwide reported in 2014. Twenty-eight percent of these cases were in the World Health Organization (WHO) Africa Region, where the annual case detection rate was 281 per 100000 population-more than double the global average of 133 per 100000. Of the 9.6 million people who developed TB, an estimated 1.2 million (12%) were HIV-positive, and the Africa Region accounted for 74% of these cases. Three million people with TB remain undiagnosed and untreated. Globally, an estimated 480000 had multidrug-resistant TB (MDR-TB). Whilst of the African countries, only South Africa has reported a high prevalence of MDR-TB, it is likely that all of Sub-Saharan Africa has an unreported high load of drug-resistant TB. Tragically, in 2014, only 48% of individuals diagnosed with MDR-TB had successful treatment and an estimated 190000 people died of MDR-TB. Of the global TB funding gap of US$ 0.8 billion, the largest funding gap was in the Africa Region, amounting to US$ 0.4 billion in 2015. The MDR-TB pandemic in particular now threatens to devastate entire regions and may fundamentally alter the life-expectancy and demographic profile of many countries in Sub-Saharan Africa. The theme designated for this year's World TB Day, March 24, 2016, is 'Unite to End TB'. From the Africa Region, there is an urgent need to seriously address the political, economic, and social factors that influence host-Mycobacterium tuberculosis interactions and result in disease. Recent political and funder initiatives that provide renewed hope for the alleviation of Africa's TB and TB/HIV problems are discussed.
DOI: 10.1016/j.ijid.2016.03.003
PubMed: 26969406
Affiliations:
- Allemagne, Ghana, Kenya, Mozambique, Oman, Ouganda, Royaume-Uni, Suède, Tanzanie, Zambie
- Angleterre, Bade-Wurtemberg, District de Tübingen, Grand Londres, Région du Grand Accra, Svealand
- Accra, Londres, Stockholm, Tübingen
Links toward previous steps (curation, corpus...)
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- to stream PubMed, to step Checkpoint: 000876
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Le document en format XML
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Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany. Electronic address: fntoumi@fcrm-congo.com.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Fondation Congolaise pour la Recherche Médicale, Brazzaville, Republic of Congo; Institute for Tropical Medicine, University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Kaleebu, Pontiano" sort="Kaleebu, Pontiano" uniqKey="Kaleebu P" first="Pontiano" last="Kaleebu">Pontiano Kaleebu</name><affiliation wicri:level="1"><nlm:affiliation>Uganda Virus Research Institute Research Unit on AIDS, Entebbe, Uganda.</nlm:affiliation><country xml:lang="fr">Ouganda</country><wicri:regionArea>Uganda Virus Research Institute Research Unit on AIDS, Entebbe</wicri:regionArea><wicri:noRegion>Entebbe</wicri:noRegion></affiliation></author><author><name sortKey="Macete, Eusebio" sort="Macete, Eusebio" uniqKey="Macete E" first="Eusebio" last="Macete">Eusebio Macete</name><affiliation wicri:level="1"><nlm:affiliation>Centro de Investigação em Saude de Manhiça, and National Directare of Public Health, Ministry of Health, Maputo, Mozambique.</nlm:affiliation><country xml:lang="fr">Mozambique</country><wicri:regionArea>Centro de Investigação em Saude de Manhiça, and National Directare of Public Health, Ministry of Health, Maputo</wicri:regionArea><wicri:noRegion>Maputo</wicri:noRegion></affiliation></author><author><name sortKey="Mfinanga, Sayoki" sort="Mfinanga, Sayoki" uniqKey="Mfinanga S" first="Sayoki" last="Mfinanga">Sayoki Mfinanga</name><affiliation wicri:level="1"><nlm:affiliation>Muhimbili Medical Research Centre, National Institute for Medical Research, Dar es Salaam, Tanzania.</nlm:affiliation><country xml:lang="fr">Tanzanie</country><wicri:regionArea>Muhimbili Medical Research Centre, National Institute for Medical Research, Dar es Salaam</wicri:regionArea><wicri:noRegion>Dar es Salaam</wicri:noRegion></affiliation></author><author><name sortKey="Chakaya, Jeremiah" sort="Chakaya, Jeremiah" uniqKey="Chakaya J" first="Jeremiah" last="Chakaya">Jeremiah Chakaya</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, Dermatology and Psychiatry, Kenyatta University, Nairobi, Kenya.</nlm:affiliation><country xml:lang="fr">Kenya</country><wicri:regionArea>Department of Medicine, Dermatology and Psychiatry, Kenyatta University, Nairobi</wicri:regionArea><wicri:noRegion>Nairobi</wicri:noRegion></affiliation></author><author><name sortKey="Yeboah Manu, Dorothy" sort="Yeboah Manu, Dorothy" uniqKey="Yeboah Manu D" first="Dorothy" last="Yeboah-Manu">Dorothy Yeboah-Manu</name><affiliation wicri:level="3"><nlm:affiliation>Noguchi Memorial Institute for Medical Research, Accra, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Noguchi Memorial Institute for Medical Research, Accra</wicri:regionArea><placeName><settlement type="city">Accra</settlement><region nuts="2">Région du Grand Accra</region></placeName></affiliation></author><author><name sortKey="Bates, Matthew" sort="Bates, Matthew" uniqKey="Bates M" first="Matthew" last="Bates">Matthew Bates</name><affiliation wicri:level="1"><nlm:affiliation>UNZA-UCLMS Research and Training Project, University Teaching Hospital, Lusaka, Zambia.</nlm:affiliation><country xml:lang="fr">Zambie</country><wicri:regionArea>UNZA-UCLMS Research and Training Project, University Teaching Hospital, Lusaka</wicri:regionArea><wicri:noRegion>Lusaka</wicri:noRegion></affiliation></author><author><name sortKey="Mwaba, Peter" sort="Mwaba, Peter" uniqKey="Mwaba P" first="Peter" last="Mwaba">Peter Mwaba</name><affiliation wicri:level="1"><nlm:affiliation>UNZA-UCLMS Research and Training Project, University Teaching Hospital, Lusaka, Zambia; Ministry of Health, Lusaka, Zambia.</nlm:affiliation><country xml:lang="fr">Zambie</country><wicri:regionArea>UNZA-UCLMS Research and Training Project, University Teaching Hospital, Lusaka, Zambia; Ministry of Health, Lusaka</wicri:regionArea><wicri:noRegion>Lusaka</wicri:noRegion></affiliation></author><author><name sortKey="Maeurer, Markus" sort="Maeurer, Markus" uniqKey="Maeurer M" first="Markus" last="Maeurer">Markus Maeurer</name><affiliation wicri:level="3"><nlm:affiliation>Division of Therapeutic Immunology, Department of Laboratory Medicine, Karolinska Institutet, and Centre for Allogeneic Stem Cell Transplantation, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Division of Therapeutic Immunology, Department of Laboratory Medicine, Karolinska Institutet, and Centre for Allogeneic Stem Cell Transplantation, Karolinska University Hospital, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Petersen, Eskild" sort="Petersen, Eskild" uniqKey="Petersen E" first="Eskild" last="Petersen">Eskild Petersen</name><affiliation wicri:level="1"><nlm:affiliation>University of Aarhus, Aarhus, Denmark; The Royal Hospital, Muscat, Oman.</nlm:affiliation><country xml:lang="fr">Oman</country><wicri:regionArea>University of Aarhus, Aarhus, Denmark; The Royal Hospital, Muscat</wicri:regionArea><wicri:noRegion>Muscat</wicri:noRegion></affiliation></author><author><name sortKey="Zumla, Alimuddin" sort="Zumla, Alimuddin" uniqKey="Zumla A" first="Alimuddin" last="Zumla">Alimuddin Zumla</name><affiliation wicri:level="3"><nlm:affiliation>UNZA-UCLMS Research and Training Project, University Teaching Hospital, Lusaka, Zambia; Division of Infection and Immunity, University College London, and NIHR Biomedical Research Centre, UCL Hospitals NHS Foundation Trust, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>UNZA-UCLMS Research and Training Project, University Teaching Hospital, Lusaka, Zambia; Division of Infection and Immunity, University College London, and NIHR Biomedical Research Centre, UCL Hospitals NHS Foundation Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></analytic><series><title level="j">International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases</title><idno type="eISSN">1878-3511</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Africa (epidemiology)</term><term>Antitubercular Agents (therapeutic use)</term><term>Disease Eradication</term><term>Global Health</term><term>HIV Seropositivity</term><term>Humans</term><term>Mycobacterium tuberculosis (drug effects)</term><term>Prevalence</term><term>Tuberculosis (epidemiology)</term><term>Tuberculosis (prevention & control)</term><term>Tuberculosis, Multidrug-Resistant (epidemiology)</term><term>Tuberculosis, Multidrug-Resistant (prevention & control)</term><term>World Health Organization</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Afrique (épidémiologie)</term><term>Antituberculeux (usage thérapeutique)</term><term>Humains</term><term>Mycobacterium tuberculosis ()</term><term>Organisation mondiale de la santé</term><term>Prévalence</term><term>Santé mondiale</term><term>Séropositivité VIH</term><term>Tuberculose ()</term><term>Tuberculose (épidémiologie)</term><term>Tuberculose multirésistante ()</term><term>Tuberculose multirésistante (épidémiologie)</term><term>Éradication de maladie</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antitubercular Agents</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Mycobacterium tuberculosis</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Africa</term><term>Tuberculosis</term><term>Tuberculosis, Multidrug-Resistant</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Tuberculosis</term><term>Tuberculosis, Multidrug-Resistant</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antituberculeux</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Afrique</term><term>Tuberculose</term><term>Tuberculose multirésistante</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Disease Eradication</term><term>Global Health</term><term>HIV Seropositivity</term><term>Humans</term><term>Prevalence</term><term>World Health Organization</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Mycobacterium tuberculosis</term><term>Organisation mondiale de la santé</term><term>Prévalence</term><term>Santé mondiale</term><term>Séropositivité VIH</term><term>Tuberculose</term><term>Tuberculose multirésistante</term><term>Éradication de maladie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Tuberculosis (TB) remains a global emergency, with an estimated 9.6 million new TB cases worldwide reported in 2014. Twenty-eight percent of these cases were in the World Health Organization (WHO) Africa Region, where the annual case detection rate was 281 per 100000 population-more than double the global average of 133 per 100000. Of the 9.6 million people who developed TB, an estimated 1.2 million (12%) were HIV-positive, and the Africa Region accounted for 74% of these cases. Three million people with TB remain undiagnosed and untreated. Globally, an estimated 480000 had multidrug-resistant TB (MDR-TB). Whilst of the African countries, only South Africa has reported a high prevalence of MDR-TB, it is likely that all of Sub-Saharan Africa has an unreported high load of drug-resistant TB. Tragically, in 2014, only 48% of individuals diagnosed with MDR-TB had successful treatment and an estimated 190000 people died of MDR-TB. Of the global TB funding gap of US$ 0.8 billion, the largest funding gap was in the Africa Region, amounting to US$ 0.4 billion in 2015. The MDR-TB pandemic in particular now threatens to devastate entire regions and may fundamentally alter the life-expectancy and demographic profile of many countries in Sub-Saharan Africa. The theme designated for this year's World TB Day, March 24, 2016, is 'Unite to End TB'. From the Africa Region, there is an urgent need to seriously address the political, economic, and social factors that influence host-Mycobacterium tuberculosis interactions and result in disease. Recent political and funder initiatives that provide renewed hope for the alleviation of Africa's TB and TB/HIV problems are discussed.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Ghana</li><li>Kenya</li><li>Mozambique</li><li>Oman</li><li>Ouganda</li><li>Royaume-Uni</li><li>Suède</li><li>Tanzanie</li><li>Zambie</li></country><region><li>Angleterre</li><li>Bade-Wurtemberg</li><li>District de Tübingen</li><li>Grand Londres</li><li>Région du Grand Accra</li><li>Svealand</li></region><settlement><li>Accra</li><li>Londres</li><li>Stockholm</li><li>Tübingen</li></settlement></list><tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Ntoumi, Francine" sort="Ntoumi, Francine" uniqKey="Ntoumi F" first="Francine" last="Ntoumi">Francine Ntoumi</name></region></country><country name="Ouganda"><noRegion><name sortKey="Kaleebu, Pontiano" sort="Kaleebu, Pontiano" uniqKey="Kaleebu P" first="Pontiano" last="Kaleebu">Pontiano Kaleebu</name></noRegion></country><country name="Mozambique"><noRegion><name sortKey="Macete, Eusebio" sort="Macete, Eusebio" uniqKey="Macete E" first="Eusebio" last="Macete">Eusebio Macete</name></noRegion></country><country name="Tanzanie"><noRegion><name sortKey="Mfinanga, Sayoki" sort="Mfinanga, Sayoki" uniqKey="Mfinanga S" first="Sayoki" last="Mfinanga">Sayoki Mfinanga</name></noRegion></country><country name="Kenya"><noRegion><name sortKey="Chakaya, Jeremiah" sort="Chakaya, Jeremiah" uniqKey="Chakaya J" first="Jeremiah" last="Chakaya">Jeremiah Chakaya</name></noRegion></country><country name="Ghana"><region name="Région du Grand Accra"><name sortKey="Yeboah Manu, Dorothy" sort="Yeboah Manu, Dorothy" uniqKey="Yeboah Manu D" first="Dorothy" last="Yeboah-Manu">Dorothy Yeboah-Manu</name></region></country><country name="Zambie"><noRegion><name sortKey="Bates, Matthew" sort="Bates, Matthew" uniqKey="Bates M" first="Matthew" last="Bates">Matthew Bates</name></noRegion><name sortKey="Mwaba, Peter" sort="Mwaba, Peter" uniqKey="Mwaba P" first="Peter" last="Mwaba">Peter Mwaba</name></country><country name="Suède"><region name="Svealand"><name sortKey="Maeurer, Markus" sort="Maeurer, Markus" uniqKey="Maeurer M" first="Markus" last="Maeurer">Markus Maeurer</name></region></country><country name="Oman"><noRegion><name sortKey="Petersen, Eskild" sort="Petersen, Eskild" uniqKey="Petersen E" first="Eskild" last="Petersen">Eskild Petersen</name></noRegion></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Zumla, Alimuddin" sort="Zumla, Alimuddin" uniqKey="Zumla A" first="Alimuddin" last="Zumla">Alimuddin Zumla</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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